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Nlr Proteins: Methods and Protocols

Nlr Proteins: Methods and Protocols

Hardcover

Series: Methods in Molecular Biology, Book 2696

Chemistry

ISBN10: 107163349X
ISBN13: 9781071633496
Publisher: Humana
Published: Aug 15 2023
Pages: 299
Weight: 1.67
Height: 0.75 Width: 7.00 Depth: 10.00
Language: English

This second edition provides a sound basis for the molecular investigation of NLR function in health and disease. Chapters focus on NLR as innate immune receptors, atypical inflammasomes, biochemical and novel bioluminescence techniques for the measurement of IL-1b as readout of NLR-based inflammasomes, bioluminescent probe, biochemical and microscopy techniques, techniques to measure caspase-1 activation, cell free systems for the study of inflammasome function, and inflammasome activation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

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Pelegrín, Pablo

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Chemistry