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Novartis Foundation Symposium 244

Novartis Foundation Symposium 244

Hardcover

Series: Novartis Foundation Symposia, Book 244

BiologyChemistryGenetics

ISBN10: 0470843462
ISBN13: 9780470843468
Publisher: John Wiley & Sons
Published: May 1 2005
Pages: 280
Weight: 1.28
Height: 0.75 Width: 6.00 Depth: 9.00
Language: English
Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice.

This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms.

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