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New Organocatalytic Strategies for the Selective Synthesis of Centrally and Axially Chiral Molecules

New Organocatalytic Strategies for the Selective Synthesis of Centrally and Axially Chiral Molecules

Paperback

Series: Springer Theses

Chemistry

ISBN10: 3030091031
ISBN13: 9783030091033
Publisher: Springer Nature
Published: Jan 26 2019
Pages: 157
Weight: 0.57
Height: 0.38 Width: 6.14 Depth: 9.21
Language: English

This thesis discusses the use of asymmetric organic catalysis for the direct enantioselective synthesis of complex chiral molecules, and by addressing the many aspects of both vinylogy and atropisomerism, it appeals to researchers and scholars interested in both areas.

Organocatalysis is a relatively modern and hot topic in the chemical community; it is constantly expanding and its use has been extended to interesting areas like vinylogous reactivity and atropisomerism. Vinylogous systems are very important for their synthetic applications but also pose a number of challenges, the most notable of which are their reduced reactivity and the reduced stereocontrol at these positions. On the other hand, atropisomeric systems are even more important because of the huge potential they have as drugs, ligands and catalysts. Chemists have only recently recognized the importance of these two areas and are focusing their efforts on studying them and the challenges they pose.

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