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Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
New epitome of human red blood cell destruction

New epitome of human red blood cell destruction

Paperback

Chemistry

ISBN10: 3659531987
ISBN13: 9783659531989
Publisher: Lap Lambert Academic Pub
Published: Jun 4 2014
Pages: 100
Weight: 0.35
Height: 0.24 Width: 6.00 Depth: 9.00
Language: English
Human erythrocytes survive in the circulation for about 120 days. How do they appreciate aging and determine their lifespan? The objective of this monograph is to present a fully new compendium (molecular-sensing) of Heinz body formation mechanisms inherent in human erythrocytes, whereby α1-β1 (and α2-β2) interface of the hemoglobin molecule (α2β2) controls removal of erythrocytes from the blood circulation by triggering degradation of the molecule to hemichrome, and subsequent clustering of Heinz bodies within the erythrocytes depending on the internal and extraneous conditions of the erythrocyte. So, Heinz body-containing red cells become trapped in the spleen and undergo hemolysis.

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Chemistry