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Modified Nucleic Acids

Modified Nucleic Acids

Hardcover

Series: Nucleic Acids and Molecular Biology, Book 31

Technology & EngineeringBiologyChemistry

ISBN10: 3319271091
ISBN13: 9783319271095
Publisher: Springer Nature
Published: Apr 11 2016
Pages: 276
Weight: 1.28
Height: 0.69 Width: 6.14 Depth: 9.21
Language: English
This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.

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