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612-822-4611
Medicinal Chemist's Guide to Solving Admet Challenges

Medicinal Chemist's Guide to Solving Admet Challenges

Hardcover

Series: Drug Discovery, Book 79

Medical ReferenceChemistry

ISBN10: 1788012275
ISBN13: 9781788012270
Publisher: Royal Society of Chemistry
Published: Aug 27 2021
Pages: 518
Weight: 2.15
Height: 1.00 Width: 6.10 Depth: 9.20
Language: English

The Medicinal Chemist's Guide to Solving ADMET Challenges summarizes a series of design strategies and tactics that have been successfully employed across pharmaceutical and academic laboratories to solve common ADMET issues. These are exemplified with a curated collection of concrete examples displayed in a highly visual table-of-contents style format, allowing readers to rapidly identify the most promising approaches applicable to their own challenges. Each ADMET parameter is introduced in a concise yet comprehensive manner and includes background, relevance and screening strategies. Medicinal chemistry knowledge of how best to modify molecular structure to solve ADMET issues is challenging to retrieve from the literature, public databases and even corporate data warehouses. The Medicinal Chemist's Guide to Solving ADMET Challenges addresses this gap by presenting state-of-the-art design strategies put together by a global group of experienced medicinal chemists and ADMET experts across academia and the pharmaceutical industry.

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Chemistry