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Mass Spectrometry: Developmental Approaches to Answer Biological Questions

Mass Spectrometry: Developmental Approaches to Answer Biological Questions

Paperback

Series: Springerbriefs in Bioengineering

Medical ReferenceTechnology & EngineeringGeneral Science

ISBN10: 3319130862
ISBN13: 9783319130866
Publisher: Springer
Published: Mar 5 2015
Pages: 71
Weight: 0.27
Height: 0.17 Width: 6.14 Depth: 9.21
Language: English

The understanding of the events taking place in a cell, a biological fluid or in any biological system is the main goal of biology research. Many fields of research use different technology to assess those events. Mass spectrometry is one of those techniques and this undergoes constant evolution and adaptation to always enhance the accuracy of the information provided. Proteomics provides a large panel of data on protein identity and protein expression that were made possible by mass spectrometry. For several years now mass spectrometry has become central to performing proteomic research, however this powerful tool is under constant evolution to be more sensitive and more resolute. More importantly mass spectrometry became a field of research focusing on new applications. Indeed, the complexity in biological systems relies on the changes of expression of transcription of proteins but also on the post-translational modification of proteins, the structure of proteins and the interaction between proteins, amongst others. As of now, several investigations tried to improve the quantification of proteins by mass spectrometry, the determination of post-translational modifications, the protein-protein and protein-nucleic acids interaction or the proteins structures.

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