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LC-MS in Drug Bioanalysis

LC-MS in Drug Bioanalysis

Hardcover

Medical ReferenceChemistryGeneral Science

ISBN10: 1461438276
ISBN13: 9781461438274
Publisher: Springer Nature
Published: Jul 16 2012
Pages: 472
Weight: 1.80
Height: 1.30 Width: 6.30 Depth: 9.20
Language: English
Clinical pharmacology plays an important role in today's medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography - mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.

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