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Kinetics and Thermodynamics of Tumor Markers 11

Kinetics and Thermodynamics of Tumor Markers 11

Paperback

Series: Kinetics and Thermodynamics of Tumor Markers (CA 19-9- CA 15-3- Afp-Sialic Acid11, Book 2

Chemistry

ISBN10: 1530649234
ISBN13: 9781530649235
Publisher: Createspace
Published: Mar 21 2016
Pages: 414
Weight: 2.10
Height: 0.85 Width: 8.50 Depth: 11.00
Language: English
This book Deals with Determination of carbohydrate antigen 15-3 (CA15-3) and carbohydrate antigen 19-9 (CA 19-9) levels in sera of patients with benign and malignant breast tumors, Development of IRMA assay for the determination of CA15-3 and CA19-9 from cytosolic tissues of benign and malignant breast tumors, Characterization of the binding of 125I-anti CA15-3 antibody with isolated human - CA15-3 in benign and malignant breast tumors, such as those of binding capacity and the effect of various factors (pH, temperature, time, halides, salts, CA15-3 and its antibody concentration), Determination of kinetic and thermodynamic parameters of the binding of partially purified CA15-3 with its specific antibody and Spectroscopic studies on (125I-anti CA15-3 antibody / CA15-3) complex in breast tissue . Further more the level of sera CA 15-3 in patients with benign and malignant breast tumors (preoperative) was measured by Immunoradiometric Assay (IRMA). Data analysis showed, concentrations of CA 15-3 were significantly higher in pre-and post-menopausal malignant breast tumors (P

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Chemistry