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Kinase Inhibitors: Methods and Protocols
Paperback
Series: Methods in Molecular Biology, Book 795
Medical ReferenceBiologyChemistry
ISBN13: 9781493957576
Publisher: Humana Pr
Published: Aug 23 2016
Pages: 256
Weight: 1.04
Height: 0.57 Width: 7.00 Depth: 10.00
Language: English
1. Targeting Cancer with Small Molecular Weight Kinase Inhibitors
Doriano Fabbro, Sandra W. Cowan-Jacob, Henrik Möbitz, and Georg Martiny-Baron
2. Small Molecule Protein and Lipid Kinase Inhibitors in Inflammation and Specific Models for their Evaluation
Matthias Gaestel and Alexey Kotlyarov
3. Measuring the Activity of Leucine Rich Repeat Kinase 2 (LRRK2) - A Kinase Involved in Parkinson's Disease
Byoung Dae Lee, Xiaojie Li, Ted M. Dawson, and Valina L. Dawson
4. Measuring PI3K Lipid Kinase Activity
Elisa Ciraolo, Alessia Perino, and Emilio Hirsch
5. A Fluorescence Polarization Assay for the Discovery of Inhibitors of the Polo-box Domain of Polo-like Kinase 1
Wolfgang Reindl, Klaus Strebhardt, and Thorsten Berg
6. Assessment of Hepatotoxicity Potential of Drug Candidate Molecules Including Kinase Inhibitors by Hepatocyte Imaging Assay Technology and Bile Flux Imaging Assay Technology
Jinghai J. Xu, Margaret C. Dunn, Arthur R. Smith, and Eric S. Tien
7. Kinase Inhibitor Selectivity Profiling using Differential Scanning Fluorimetry
Oleg Fedorov, Frank H. Niesen, and Stefan Knapp
8. Chemoproteomic Characterization of Protein Kinase Inhibitors using Immobilized ATP
James S. Duncan, Timothy A.J. Haystead, and David W. Litchfield
9. Proteome-wide identification of staurosporine-binding kinases using Capture Compound Mass Spectrometry
Jenny J. Fischer, Olivia Y. Graebner neé Baessler, and Mathias Dreger
10. Affinity Purification of Proteins Binding to Kinase Inhibitors Immobilised on Self Assembling Monolayers
Marcus Bantscheff, Scott Hobson, and Bernhard Kuster
11. Kinase Inhibitor Profiling using Chemoproteomics
Markus Schirle, Eugene C. Petrella, Scott M. Brittain, David Schwalb, Edmund Harrington, Ivan Cornella-Taracido, and John A. Tallarico
12. Covalent Crosslinking of Kinases with Their Corresponding Peptide Substrates
Alexander V. Statsuk and Kevan M. Shokat
13. Receptor Tyrosine Kinase Inhibitor Profiling using Bead-based Multiplex Sandwich Immunoassays
Oliver Pötz, Nicole Schneiderhan-Marra, Tanja Henzler, Thomas Herget, and Thomas O. Joos
14. Monitoring Phosphoproteomic Response To Targeted Kinase Inhibitors Using Reverse-Phase Protein Microarrays
Gabriela Lavezzari and Mark R. Lackner
15. Measuring Phosphorylation Specific Changes in Response to Kinase Inhibitors in Mammalian Cells Using Quantitative Proteomics
Nurhan Özlü, Marc Kirchner, and Judith Jebanathirajah Steen
16. Investigation of Acquired Resistance to EGFR-Targeted Therapies in Lung Cancer Using cDNA Microarrays
Kian Kani, Rafaella Sordella, and Parag Mallick
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