Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
612-822-4611

  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Immunobiology of Proteins and Peptides - I

Immunobiology of Proteins and Peptides - I

Atassi, M. Zouhair

Paperback

Series: Advances in Experimental Medicine and Biology, Book 98

Medical ReferenceOther Animals

ISBN10: 146158860X
ISBN13: 9781461588603
Publisher: Springer Nature
Published: Nov 25 2012
Pages: 513
Weight: 1.82
Height: 1.05 Width: 6.69 Depth: 9.61
Language: English
One of the central questions in immunology is the understanding in molecular terms of antigen-antibody interactions and of the cellu- lar recognition of antigens. It is hoped that this understanding will extend eventually to the immunobiological basis of host defense to infectious agents and of tissue damage or deranged cell functions which stem from these reactions. A variety of natural and artificial substances have been used as models for these studies. Emphasis was placed upon substances of known and relatively uncomplicated chemical structures. These included polysaccharides, amino acid polymers, nu- cleic acids and haptens. On the other hand. until recently there has been very little information on protein antigens. The complexity of these molecules posed an immense chemical obstacle to precise immuno- chemical analysis. Indeed, it is this difficulty with proteins that spurred the synthesis and immunological studies of amino acid poly- mers. The control and normal regulation of the immune system at the cellular-molecular interface and the great majority of antigens asso- ciated with immune disorders are attributed to protein molecules. In the last few years great advances have been made in the analysis and synthesis of the antigenic sites of some proteins. The entire antigenic structures of myoglobin and lysozyme and the partial anti- genic structures of several other proteins have been determined. Moreover, in the past seven years several biological responses resulting from the reactions of proteins and their peptides with cells of the immune system were described.

Also in

Other Animals

View All