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A Hidden Legacy: The Life and Work of Esther Zimmer Lederberg

A Hidden Legacy: The Life and Work of Esther Zimmer Lederberg

Hardcover

Biographies GeneralSports GeneralEvolution

ISBN10: 0197531679
ISBN13: 9780197531679
Publisher: Oxford University Press
Published: Aug 31 2021
Pages: 176
Weight: 0.86
Height: 0.79 Width: 6.37 Depth: 9.67
Language: English
It's time to honor the significant scientific contributions of Esther Zimmer Lederberg. In A Hidden Legacy, Thomas E. Schindler shares the story of this remarkable microbiologist and offers insight into why her legacy has been obscured for so long.

In the mid-20th century, microbiologist Esther Zimmer Lederberg and her then-husband, Joshua Lederberg, made a series of remarkable discoveries that contributed to the biochemical understanding of the gene. Together, they laid the foundation for molecular biology and the field of bacterial genetics. In 1958, he alone was awarded the Nobel Prize for their work. Esther's ingenuity was largely ignored and undervalued by the Nobel committee and has continued to be obscured by historians of science.

In this book, Thomas E. Schindler shares many of Esther's hidden scientific contributions and her role in the discoveries that launched her then-husband's celebrated career. A Hidden Legacy delves into how, as a couple, the Lederbergs established a new field of bacterial genetics in the decade leading up to the discovery of the DNA double helix. Their impressive series of achievements includes the discovery of: λ bacteriophage and the first plasmid, known as the F-factor; how viruses carry bacterial genes between bacteria; and fundamental properties of bacterial sex. Schindler explains how Esther's research revealed unique features of bacterial sex that are now essential to our understanding of molecular biology and evolution.

A magnificent story of a remarkable scientist, A Hidden Legacy takes readers through the process that scrambled the tree of life and offers insight into the role Esther played in uncovering these secretes of bacterial and viral genes.

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