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Heterologous Expression of Membrane Proteins: Methods and Protocols

Heterologous Expression of Membrane Proteins: Methods and Protocols

Paperback

Series: Methods in Molecular Biology, Book 1432

BiologyChemistry

ISBN10: 1493981021
ISBN13: 9781493981021
Publisher: Humana
Published: May 30 2018
Pages: 322
Weight: 1.29
Height: 0.70 Width: 7.00 Depth: 10.00
Language: English

This detailed volume encompasses chapters from leading experts in the area of membrane proteins who describe step-by-step protocols developed these last few years to improve the functional production and stabilization of recombinant integral membrane proteins (IMPs). Membrane proteins play a key role in numerous pathologies such as cancer, cystic fibrosis, epilepsy, hyperinsulinism, and Alzheimer's disease, yet studies on these and other disorders are hampered by a lack of information about the proteins involved. This book sets out to aid researchers in rectifying this situation. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

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