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Hdac/Hat Function Assessment and Inhibitor Development: Methods and Protocols

Hdac/Hat Function Assessment and Inhibitor Development: Methods and Protocols

Paperback

Series: Methods in Molecular Biology, Book 1510

BiologyChemistry

ISBN10: 1493982265
ISBN13: 9781493982264
Publisher: Humana
Published: Jun 20 2018
Pages: 415
Weight: 1.64
Height: 0.88 Width: 7.00 Depth: 10.00
Language: English
This detailed collection covers how the biological functions of histone deacetylases (HDACs) and histone acetyltransferases (HATs) can be detected in various experimental settings, both in vivo and in vitro. The book also covers the generation and specificity of deacetylase inhibitors and how such agents can be used to test experimental hypotheses. Written for the popular Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.

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