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Histopathologische Wirkung von Aluminiumchlorid auf die Niere von Kaninchen
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ISBN10: 6209014879
ISBN13: 9786209014871
Publisher: Verlag Unser Wissen
Published: Aug 23 2025
Pages: 80
Weight: 0.26
Height: 0.19 Width: 6.00 Depth: 9.00
Language: German
ISBN13: 9786209014871
Publisher: Verlag Unser Wissen
Published: Aug 23 2025
Pages: 80
Weight: 0.26
Height: 0.19 Width: 6.00 Depth: 9.00
Language: German
Die vorliegende Studie wurde durchgeführt, um die zeitabhängige toxische Wirkung einer subletalen Dosis oral verabreichtem Aluminiumchlorid bei männlichen Kaninchen (Oryctolagus cuniculus) auf die Histologie des Nierengewebes zu untersuchen. Die Tiere wurden in eine Kontrollgruppe und eine behandelte Gruppe aufgeteilt. Die Tiere der behandelten Gruppe erhielten 15 bzw. 30 Tage lang alle 48 Stunden eine Dosis von 25 mg/kg Aluminiumchlorid, gelöst in 0,9 %iger Kochsalzlösung, während die Tiere der Kontrollgruppe nur 0,9 %ige Kochsalzlösung erhielten. Die Tiere wurden im Abstand von 15 Tagen seziert. Das Nierengewebe wurde für histologische Untersuchungen aufbereitet und mit Hämatoxylin und Eosin gefärbt. Es wurden histologische Veränderungen im Nierengewebe der behandelten Tiere beobachtet. Das grundlegende Ziel dieser Untersuchung war es, die Toxizität von Aluminiumchlorid in den Nieren von Kaninchen zu untersuchen.
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