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Functional Genomics: Methods and Protocols

Functional Genomics: Methods and Protocols

Hardcover

Series: Methods in Molecular Biology, Book 224

Medical ReferenceChemistry

ISBN10: 1588292916
ISBN13: 9781588292919
Publisher: Springer Nature
Published: Mar 13 2003
Pages: 260
Weight: 1.10
Height: 0.80 Width: 6.10 Depth: 9.10
Language: English
This collection of robust, readily reproducible methods for microarray-based studies includes expert guidance in the optimal data analysis and informatics. On the methods side are proven techniques for monitoring subcellular RNA localization en masse, for mapping chromosomes at the resolution of a single gene, and for surveying the steady-state genome-wide distribution of DNA binding proteins in vivo. For those workers dealing with massive data sets, the book discusses the methodological aspects of data analysis and informatics in the design of microarray experiments, the choice of test statistic, and the assessment of observational significance, data reduction, and clustering.

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