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Endocytosis
Hardcover
Series: Cold Spring Harbor Perspectives in Biology
BiologyChemistryGeneral Science
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ISBN13: 9781621820246
Publisher: Cold Spring Harbor Laboratory Press
Published: Mar 31 2014
Pages: 590
Weight: 3.15
Height: 1.10 Width: 7.17 Depth: 10.24
Language: English
neurotransmission, and antigen presentation. Pathogens (e.g., HIV) exploit endocytic pathways to gain entry into cells, and defects in the endocytic machinery can lead to diseases such as cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology covers all of the major pathways of endocytosis and postendocytic trafficking and how they regulate cellular and organismal physiology. Contributors describe how cargo enters the cell via
endosomes and deliver it to lysosomes or recycle it back to the cell surface, and the signals and mechanisms governing these sorting decisions. Topics such as lysosomal dynamics, the biophysical challenges of bending membranes, and the evolution of endocytic systems are also covered. This volume also includes substantial discussion of the roles of endocytic trafficking in organismal development, physiology, and disease. It is thus an indispensable reference for cell biologists, but also for neuroscientists, immunologists, developmental biologists, microbiologists, and others
concerned with the physiological and therapeutic implications of this key cellular process.
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