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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Excitatory Amino Acids and Epilepsy

Excitatory Amino Acids and Epilepsy

Schwarcz, Robert
Ben-Ari, Yehezkel

Paperback

Series: Advances in Experimental Medicine and Biology, Book 203

Chemistry

ISBN10: 1468479733
ISBN13: 9781468479737
Publisher: Springer Nature
Published: Nov 26 2012
Pages: 735
Weight: 2.83
Height: 1.50 Width: 7.00 Depth: 10.00
Language: English
Human epilepsy is a major public health problem affecting approximately 2 persons per 1000. It is particularly frequent in ohildren where convul- sions may lead to brain damage and subsequent seizure activity in adulthood. Temporal lobe epilepsy (synonyms include limbic epilepsy. psychomotor epilepsy and complex partial epilepsy) is the most devastating form of epilepsy in the adult population since: a) it is often extremely resistant to currently available anticonvulsant drugs (i.e -- it is more resistant than tonico-clonic or grand mal seizures) and b) it includes loss of consciousness. thereby limiting performance of many normal functions and leaving the individual susceptible to bodily injury. It is also associated with nerve cell loss. in particular in the hippocampus and other structures of the temporal lobes. In order to promote an appropriate therapy it is essential to understand the etiology of seizures and its relationship to brain damage. Basic research on epilepsy also provides a very useful vehicle to learn about the way the brain functions under normal conditions. For instance. much of our present understanding of the mechanisms of action of GABA and benzo- diazepines. control of neuronal activity. etc. has been derived from such stUdies.

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