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612-822-4611
Epigenomics: From Chromatin Biology to Therapeutics

Epigenomics: From Chromatin Biology to Therapeutics

Paperback

ChemistryGenetics

ISBN10: 1107697832
ISBN13: 9781107697836
Publisher: Cambridge University Press
Published: Jul 10 2014
Pages: 574
Weight: 1.99
Height: 1.16 Width: 6.69 Depth: 9.61
Language: English
Understanding mechanisms of gene regulation that are independent of the DNA sequence itself - epigenetics - has the potential to overthrow long-held views on central topics in biology, such as the biology of disease or the evolution of species. High throughput technologies reveal epigenetic mechanisms at a genome-wide level, giving rise to epigenomics as a new discipline with a distinct set of research questions and methods. Leading experts from academia, the biotechnology and pharmaceutical industries explain the role of epigenomics in a wide range of contexts, covering basic chromatin biology, imprinting at a genome-wide level, and epigenomics in disease biology and epidemiology. Details on assays and sequencing technology serve as an up-to-date overview of the available technological tool kit. A reliable guide for newcomers to the field as well as experienced scientists, this is a unique resource for anyone interested in applying the power of twenty-first-century genomics to epigenetic studies.

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