Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Easy Ways to Understand HPLC, UV and Method Validation Parameters

Easy Ways to Understand HPLC, UV and Method Validation Parameters

Chowdhury, Mazharul Islam

Paperback

General Mathematics

ISBN10: 3659402397
ISBN13: 9783659402395
Publisher: Lap Lambert Academic Pub
Published: May 25 2013
Pages: 52
Weight: 0.20
Height: 0.12 Width: 6.00 Depth: 9.00
Language: English
High-pressure liquid chromatography (HPLC) used in the analytical development to quantify the biological sample concentration, the active pharmaceutical ingredient (API) and to evaluate the impurity and degradation product profiles of the drug substances (DS) and drug products (DP). Additional uses of HPLC include determination of content uniformity of dosage form, monitoring of dissolution profiles, determination of antioxidants and preservative content and supporting of cleaning validations. UV spectroscopy is one of the most frequent used techniques in pharmaceutical analysis. It involves the measurement of UV radiation absorbed by a substance in solution. The wavelength range of UV radiation is 200-400nm (180-380 nm) and the UV radiation has a sufficient energy to excite valance electrons in many atoms or molecules; consequently, UV is involved with electronic excitation.

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