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612-822-4611
The Double [3]2] Photocycloaddition Reaction

The Double [3]2] Photocycloaddition Reaction

Hardcover

Series: Springer Theses, Book 0

Chemistry

ISBN10: 3642228593
ISBN13: 9783642228599
Publisher: Springer Nature
Published: Aug 31 2011
Pages: 184
Weight: 1.01
Height: 0.50 Width: 6.14 Depth: 9.21
Language: English
Jason Woolford's thesis describes for the first time, a double [3]2] photocycloaddition of alkenes onto aromatic rings. Modern synthetic chemistry relies on the ability of researchers to uncover new and more efficient ways of creating highly complex structures. This work describes a novel, environmentally friendly photochemical step that converts in one pot, trivial starting materials into otherwise difficult to construct fenstrane frameworks. The rigid cores of these frameworks have significant potential in drug design. Moreover, the novelty of this work overtakes many other methods for the creation of chiral centres. No less than seven chiral centres are created in the photochemical step together with the formation of four carbon-carbon bonds and multifused rings. Jason's innovative work has been the subject of several publications in peer-reviewed journals.

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Chemistry