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Development of Selective Dna-Interacting Ligands: Understanding the Function of Non-Canonical DNA Structures

Development of Selective Dna-Interacting Ligands: Understanding the Function of Non-Canonical DNA Structures

Hardcover

Series: Springer Theses

ChemistryGenetics

ISBN10: 9811577153
ISBN13: 9789811577154
Publisher: Springer Nature
Published: Sep 17 2020
Pages: 111
Weight: 0.79
Height: 0.38 Width: 6.14 Depth: 9.21
Language: English
1. General Introduction.- 2. Sequence-specific DNA alkylation and transcriptional inhibition by long-chain hairpin pyrrole-imidazole polyamide-chlorambucil conjugates targeting CAG/CTG trinucleotide repeats.- 3. Ligand-Mediated G-Quadruplex Induction in a Double-Stranded DNA Context by Cyclic Imidazole/Lysine Polyamide.- 4. Simultaneous Binding of Hybrid Molecules Constructed with Dual DNA-Binding Components to a G-Quadruplex and Its Proximal Duplex.

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