Open Daily: 10am - 10pm | Alley door pickup 10am - 7pm 3038 Hennepin Ave Minneapolis, MN
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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Detection of pathogenic infections in neurological disorders through recycling of gene expression data

Detection of pathogenic infections in neurological disorders through recycling of gene expression data

Liebhoff, Anna-Maria

Paperback

General Computers

ISBN10: 3736974094
ISBN13: 9783736974098
Publisher: Cuvillier
Published: Jun 21 2021
Pages: 142
Weight: 0.39
Height: 0.30 Width: 5.83 Depth: 8.27
Language: English
For increasing the knowledge about small RNA an online platform was built in this thesis, homogenizing the analysis of sequencing data from over 4,000 samples collected in different laboratories worldwide from various organisms. Consequentially, tissue and disease specific biomarkers were detected and evidence was found for bacterial and viral infections of the sequenced tissues. This motivated the development of an algorithm for analyzing non-host RNA sequencing reads for detecting pathogenic abundance in the host. Focusing on neurological diseases, bacterial presence is suggested in brains of dementia patients. The platform and the algorithm can help scientists to add important leads to their own studies.

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