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Cyclic Peptides: From Bioorganic Synthesis to Applications

Cyclic Peptides: From Bioorganic Synthesis to Applications

Hardcover

Series: Chemical Biology, Book 6

BiologyChemistry

ISBN10: 1782625283
ISBN13: 9781782625285
Publisher: Royal Society of Chemistry
Published: Dec 15 2017
Pages: 380
Weight: 1.60
Height: 1.10 Width: 6.30 Depth: 9.30
Language: English

Cyclic peptides are increasingly employed as chemical tools in biology and drug discovery. They have gained a lot of interest as alternative sources of new drugs to traditional small molecules.
This book introduces cyclic peptides and provides a thorough overview of biosynthetic and fully synthetic approaches to their preparation. Following an introduction to cyclic peptides, biosynthetic and traditional chemical routes to cyclic peptides are reviewed. Due to their size, their synthesis is not trivial. Recent advances in the incorporation of novel structural units are presented in addition to how synthesis and biological methods can be combined. The chemical analysis of this molecular class is also discussed. Furthermore, chapters detail the progression of cyclic peptides as tools in biology and as potential drugs, providing a future vision of their importance.

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Chemistry