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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Cyclic Adp-Ribose and Naadp: Structures, Metabolism and Functions

Cyclic Adp-Ribose and Naadp: Structures, Metabolism and Functions

Hon Cheung Lee

Hardcover

Medical ReferenceBiologyChemistry

ISBN10: 1402072813
ISBN13: 9781402072819
Publisher: Springer Nature
Published: Nov 30 2002
Pages: 460
Weight: 2.01
Height: 1.26 Width: 6.36 Depth: 9.52
Language: English
In the past decade we have witnessed the birth and maturing of a field of research centering on the Ca2+ signaling functions of cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP), which structures and mechanisms of action are truly unique among all Ca2+ messengers. A wide range of physiological functions are now known to be mediated by them in cells spanning three biological kingdoms from protist, plant to animal. This is the first book devoted entirely to the field. The story behind the emergence of the field is told and followed by comprehensive reviews of the enzymology, regulations and gene structures of ADP-ribosyl cyclases responsible for metabolizing cADPR and NAADP. Also covered is some of the current methodology developed for and widely used in the field. The rest of the book focuses on and details the Ca2+ signaling mechanisms and specific physiological functions of these two messengers in various cellular systems.

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