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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Bioactive Heterocycles III

Bioactive Heterocycles III

Khan, Mahmud T. H.

Hardcover

Series: Topics in Heterocyclic Chemistry, Book 9

Chemistry

ISBN10: 3540734015
ISBN13: 9783540734017
Publisher: Springer Nature
Published: Oct 26 2007
Pages: 287
Weight: 1.42
Height: 0.81 Width: 6.39 Depth: 9.38
Language: English
Bioactive Heterocycles III provides readers with a comprehensive overview of the most recent breakthroughs in the ?eld of heterocycles. This volume contains 8 chapters written by experts in their respective ?elds from all over the world. The chapters summarize years of extensive research in each area, andprovideinsightinthenewthemesofnaturalproductresearch.Manyofthe contributors illustrate their laboratory experiences. It's obvious that readers will gain exciting and essential information fromthe volume. In the ?rst chapter, Kayser et al. describe the chemistry, biosynthesis and biological activities of artemisinin, one of the most promising antimalarial molecules, and its related natural peroxides. They present new strategies of producing artemisinin that utilize fascinating technologies. as Additionally, thepharmacokineticpro?leandthedevelopmentofnewdrugdeliverysystems onPlasmodium infected erythrocytesare presented . Khan describes some aspects of sugar-derived heterocycles and their p- cursors which are utilized as the inhibitors against glycogen phosphorylases (GPs), and are responsible for the release of mono-glucose from poly-glucose (glycogen) in the second chapter. The inhibitors of GP could help to stop or slowdownglycogenolysisaswellasglucoseproduction.Ultimately, thewhole processwill result in the recovery fromdiabetes of NIDDMpatients. In his contribution, Verma studies quantitative structure-activityrelati- ship (QSAR) and proposes several interesting QSAR models of heterocyclic molecules having cytotoxicactivities against different cancer cell lines, which couldin turn clarify the chemical-biologicalinteractions ofsuch compounds. Alamgir et al., in the fourth chapter, review the recent progress of the synthesis, reactivity and biological activities of benzimidazoles. Additionally, they describe several new techniques and procedures for the synthesis of the same scaffold. Inthe?fthchapter, KhanreviewstheessentialroleoftheenzymeTyrosinase in human melanin production, covering various related clinical problems.

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