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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Antigen Antibody Interactions

Antigen Antibody Interactions

Delisi, C.

Paperback

Series: Lecture Notes in Biomathematics, Book 8

General Mathematics

ISBN10: 3540076972
ISBN13: 9783540076971
Publisher: Springer Nature
Published: Jun 1 1976
Pages: 142
Weight: 0.56
Height: 0.33 Width: 6.69 Depth: 9.61
Language: English
1. 1 Organization of the Immune System One of the most important survival mechanisms of vertebrates is their ability to recognize and respond to the onslaught of pathogenic microbes to which they are conti- ously exposed. The collection of host cells and molecules involved in this recognition- 12 response function constitutes its immune system. In man, it comprises about 10 cells 20 (lymphocytes) and 10 molecules (immunoglobulins). Its ontogenic development is c- strained by the requirement that it be capable of responding to an almost limitless variety of molecular configurations on foreign substances, while simultaneously remaining inert to those on self components. It has thus evolved to discriminate, with exquisite precision, between molecular patterns. The foreign substances which induce a response, called antigens, are typically large molecules such as proteins and polysaccharides. The portions of these with which immunoglobulins interact are called epitopes or determinants. A typical protein epitope may consist of a configuration formed by the spatial arrangements of four or five amino acids and have an average linear dimension of about 20 A.

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