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  • Open Daily: 10am - 10pm
    Alley-side Pickup: 10am - 7pm

    3038 Hennepin Ave Minneapolis, MN
    612-822-4611

Open Daily: 10am - 10pm | Alley-side Pickup: 10am - 7pm
3038 Hennepin Ave Minneapolis, MN
612-822-4611
Accessibility to Construct Fused or Binary Heterocyclic Compounds

Accessibility to Construct Fused or Binary Heterocyclic Compounds

Hamama, Wafaa S.
Zoorob, Hanafi H.
Gouda, Moustafa A.

Paperback

Chemistry

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ISBN10: 3659148989
ISBN13: 9783659148989
Publisher: Lap Lambert Academic Pub
Published: Jun 18 2012
Pages: 112
Weight: 0.39
Height: 0.27 Width: 6.00 Depth: 9.00
Language: English
This book highlighted the methods used for the syntheses of thiadiazole compounds. The activity of thiadiazole and their synthetic importance were investigated. It also reported a theoretically study for the expected tautomeric behavior of 2-amino(imino)-1,3,4-thiadiazole to determine if it is acting either as amine or as semicyclic amidine. In this context, we reported herein the behavior of 2-aminothiadiazole towards some active reagents as a facile and convenient route to some fused or binary heterocyclic compounds containing a thiadiazole moiety. The methods of synthesis and the synthetic mechanisms of the aforementioned reactions were well presented and the structures of these compounds were assessed by analytical and spectral data. ABTS Antioxidant assay, Bleomycin-dependent DNA damage and antitumor activity methods were used for the evaluation of the biological activity of the investigated compounds.

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