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2-Cyanoamines: Versatile Intermediates for Carboxamide Linkage Formation and Nitrogen-Containing Cyclic Systems Construction
Paperback
Technology & EngineeringGeneral ComputersGeneral Science
Publisher: Independent Publisher
Published: Jan 31 2025
Pages: 240
Weight: 1.25
Height: 0.51 Width: 8.50 Depth: 11.00
Language: English
Over 160 years after the first formation of α-aminonitrile documented, it still carries a huge attention among the organic and medicinal chemists and employed as a powerful synthetic tool for nitrogen based organic compounds [1 - 6]. It is a versatile bifunctional intermediate with an ideal combination of amine and nitrile functionality in same carbon. α-aminonitrile motif themselves have found to be in many complex bioactive natural products [7 - 9], at same time as a key intermediate to many biochemical pathways and late stage synthetic approaches [10 - 13]. This beneficial synthetic intermediate still carries a potential to provide a plenty of opportunities for the establishment of innovative and effective synthetic methodologies.
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