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ß-Barrel Channel Proteins as Tools in Nanotechnology: Biology, Basic Science and Advanced Applications

ß-Barrel Channel Proteins as Tools in Nanotechnology: Biology, Basic Science and Advanced Applications

Hardcover

Series: Advances in Experimental Medicine and Biology, Book 794

Medical ReferenceBiologyChemistry

ISBN10: 9400774281
ISBN13: 9789400774285
Publisher: Springer Nature
Published: Nov 13 2013
Pages: 168
Weight: 1.35
Height: 0.70 Width: 7.20 Depth: 10.10
Language: English
-barrel outer membrane channel proteins (OMP) are useful as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. It gives a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel will be outlined. An exhaustive description of the scientific strategy, including protein selection, analytical methods and in-silico tools to support the planning of protein modifications for a targeted application, consideration on the production of a custom made OMP, and an overview on technological applications including membrane/polymersome technology, will be provided.

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