Pharmacology Specific Aspects
The Ayahuasca Experience: A Sourcebook on the Sacred Vine of Spirits
The Ayahuasca Experience
A Sourcebook on the Sacred Vine of Spirits
Paperback      ISBN: 1620552620
An exploration of the chemical, biological, psychological, and experiential dimensions of ayahuasca • Details the scientific discovery of ayahuasca’s sophisticated psychoactive delivery system in the brain and body and its potential applications in medicine and psychology • Includes contributions from Dennis J. McKenna, Ph.D., J. C. Callaway, Ph.D., and Charles S. Grob, M.D., on the ethnopharmacology, psychology, phytochemistry, and neuropharmacology of ayahuasca • Provides 24 firsthand accounts of ayahuasca experiences and resulting life changes Widely recognized by anthropologists as the most powerful and widespread shamanic hallucinogen, ayahuasca has been used by native Indian and mestizo shamans in Peru, Colombia, and Ecuador for healing and divination for thousands of years. Made from the Amazonian vine Banisteriopsis caapi and the DMT-laden leaf of Psychotria viridis, ayahuasca is regarded as the embodiment of intelligent plant beings who can offer spiritual teachings and healing knowledge to those who respectfully engage with them. Many Western-trained physicians and psychologists now acknowledge that ayahuasca allows access to spiritual dimensions of consciousness, otherworldly realms and beings, and visionary experiences indistinguishable from classic religious mysticism. With contributions from leading psychoactive scholars Dennis J. McKenna, Ph.D., Charles S. Grob, M.D., and J. C. Calloway, Ph.D., on the ethnopharmacology, psychology, phytochemistry, and neuropharmacology of ayahuasca, Ralph Metzner provides a comprehensive exploration of the chemical, biological, psychological, and experiential dimensions of this Amazonian hallucinogen. He includes more than 20 firsthand accounts from people who have participated in ayahuasca rituals and experienced major life changes as a result. He details the scientific discovery of ayahuasca’s sophisticated psychoactive delivery system in the brain and body as well as the deep psychological impact of this potent entheogen. He concludes with his own findings on ayahuasca, including its applications in medicine and psychology, and compares the worldview revealed by ayahuasca visions to that of modern cultures.
The Acid Diaries: A Psychonaut's Guide to the History and Use of LSD
The Acid Diaries
A Psychonaut's Guide to the History and Use of LSD
Paperback      ISBN: 1594773831
An exploration of the personal and spiritual truths revealed through LSD • Reveals that LSD visions weave an ongoing story from trip to trip • Shows that trips progress through three stages: personal issues and pre-birth consciousness, ego-loss, and on to the sacred • Explores psychedelic use throughout history, including the mass hallucinations common in the Middle Ages and the early therapeutic use of LSD Toward the end of his fifties, Christopher Gray took, for the first time in years, a 100-microgram acid trip. So extraordinary, and to his surprise so enjoyable, were the effects that he began to take the same dose in the same way--quietly and on his own--once every two to three weeks. In The Acid Diaries, Gray details his experimentation with LSD over a period of three years and shares the startling realization that his visions were weaving an ongoing story from trip to trip, revealing an underlying reality of personal and spiritual truths. Following the theories of Stanislav Grof and offering quotes from others’ experiences that parallel his own--including those of Aldous Huxley, Albert Hofmann, and Gordon Wasson--he shows that trips progress through three stages: the first dealing with personal issues and pre-birth consciousness; the second with ego-loss, often with supernatural overtones; and the third with sacred, spiritual, and even apocalyptic themes. Pairing his experiences with an exploration of psychedelic use throughout history, including the ergot-spawned mass hallucinations that were common through the Middle Ages and the early use of LSD for therapeutic purposes, Gray offers readers a greater understanding and appreciation for the potential value of LSD not merely for transpersonal growth but also for spiritual development.
ADHD Medications: History, Science, and Issues
ADHD Medications
History, Science, and Issues
1st Edition    Hardcover      ISBN: 1610697251
The treatment of attention deficit/hyperactivity disorder (ADHD) is a complex challenge. This book provides comprehensive, scientific coverage of the numerous different types of drugs that are used to treat ADHD, and it examines the historical, sociological, and policy-related factors involved in the use of ADHD medications.
Adrenaline
Adrenaline
1st Edition    Hardcover      ISBN: 0674050886
Inducing highs of excitement, anger, and terror, adrenaline fuels the extremes of human experience. A rush empowers superhuman feats in emergencies. Risk-taking junkies seek to replicate this feeling in dangerous recreations. And a surge may literally scare us to death. Adrenaline brings us up to speed on the fascinating molecule that drives some of our most potent experiences. Adrenaline was discovered in 1894 and quickly made its way out of the lab into clinics around the world. In this engrossing account, Brian Hoffman examines adrenaline in all its capacities, from a vital regulator of physiological functions to the subject of Nobel Prize–winning breakthroughs. Because its biochemical pathways are prototypical, adrenaline has had widespread application in hormone research leading to the development of powerful new drugs. Hoffman introduces the scientists to whom we owe our understanding, tracing the paths of their discoveries and aspirations and allowing us to appreciate the crucial role adrenaline has played in pushing modern medicine forward. Hoffman also investigates the vivid, at times lurid, place adrenaline occupies in the popular imagination, where accounts of its life-giving and lethal properties often leave the realm of fact. Famous as the catalyst of the “fight or flight
The Alkaloids: Chemistry and Pharmacology
The Alkaloids
Chemistry and Pharmacology
Hardcover      ISBN: 0124695426
This volume deals for the most part, with current status of four groups of alkaloids of substantial biological releavance. Chapter 1 by Lounasmaa and Tolvanen, focuses on the "Eburanmine-Vincamine Alkaloids," and discusses the new alkaloids, and the extensive synthetic and pharmacologic work that has been conducted since the last review in 1981. Clark and Hufford present a review which focuses on the "Antifungal Alkaloids," especially those compounds that might be important as lead structures for the development of agents usefulin treating the opportunistic infections associated with AIDS. Wang and Liang bring up-to-date the area of the diterpenoid alkaloids from a chemical perspective. Over the years this large group of alkaloids has produced a fascinating array of molecular gyrations. Finally, Wrobel and Wojtasiewicz revisit the topic of "Sulfur-Containing Alkaloids" (which was last covered in Volume 26) from a chemical and biological perspective.
The Alkaloids: Chemistry and Pharmacology
The Alkaloids
Chemistry and Pharmacology
Hardcover      ISBN: 0124695450
Internationally acclaimed for more than 40 years, this serial, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine origins, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids, Chemistry and Pharmacology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.
The Alkaloids: Chemistry and Pharmacology
The Alkaloids
Chemistry and Pharmacology
Hardcover      ISBN: 0124695485
Internationally acclaimed for more than forty years, this Series, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structureelucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this Series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile. Key Features * Indispensible reference work written by leading experts in the field * Provides up-to-date, timely reviews on compounds and classes of great interest * Covers synthesis, biosynthesis, biology, as well as isolation and structure elucidation * An essential research tool for anyone working with alkaloids from a chemical or biological perspective
The Alkaloids: Chemistry and Biology
The Alkaloids
Chemistry and Biology
Hardcover      ISBN: 0124695507
Chemistry and Biology is a celebration of the outstanding contributions to the field by Professor R.H.F. Manske, who founded the series in 1950. This special volume demonstrates the dramatic changes in alkaloidchemistry since then. It also offers a unique overview of recent developments in major areas of alkaloid chemistry and biology and looks at how these areas will develop in the future. These fourteen contributions are written by many of the leading alkaloid chemists in the world, and thus comprise a unique view of alkaloids and their contributions to the health and well-being of humankind. Key Features * Indispensable reference work written by leading experts in the field * Provides up-to-date, timely reviews on compounds and classes of great interest * Covers synthesis, biosynthesis, biology, as well as isolation and structure elucidation * An essential research tool for anyone working with alkaloids from a chemical or biological perspective
The Alkaloids: Chemistry and Pharmacology
The Alkaloids
Chemistry and Pharmacology
Hardcover      ISBN: 0124695493
Internationally acclaimed for more than 40 years, this Series, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structure elucidation, synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this Series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all naturalproduct chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile. Key Features * Indispensable reference work written by leading experts in the field * Provides up-to-date, timely reviews on compounds and classes of great interest * Covers synthesis, biosynthesis, biology, as well as isolation and structure elucidation * An essential research tool for anyone working with alkaloids from a chemical or biological perspectiveperspective
The Alkaloids: Chemistry and Biology
The Alkaloids
Chemistry and Biology
Hardcover      ISBN: 0124695515
Chemistry and Biology is a celebration of the outstanding contributions to the field by Professor R.H.F. Manske, who founded the series in 1950. This special volume demonstrates the dramatic changes in alkaloidchemistry since then. It also offers a unique overview of recent developments in major areas of alkaloid chemistry and biology and looks at how these areas will develop in the future. These fourteen contributions are written by many of the leading alkaloid chemists in the world, and thus comprise a unique view of alkaloids and their contributions to the health and well-being of humankind. Key Features * Unique contributions from twenty of the world's leading alkaloid chemists * Critical reviews of the major progress in alkaloid chemistry * Considered commentary on the future of alkaloid chemistry * State-of-the-art insight into the role of alkaloids in the health sciences, biotechnology, and the elucidation of fundamental biological processes