Vaccines
The Vaccine Race: Science, Politics, and the Human Costs of Defeating Disease
The Vaccine Race
Science, Politics, and the Human Costs of Defeating Disease
Paperback      ISBN: 0143111310
A real jewel of science history...brims with suspense and now-forgotten catastrophe and intrigue...Wadman's smooth prose calmly spins a surpassingly complicated story into a real tour de force.--The New York Times

"Riveting . . . The Vaccine Race] invites comparison with Rebecca Skloot's 2007 The Immortal Life of Henrietta Lacks."--Nature

The epic and controversial story of a major breakthrough in cell biology that led to the conquest of rubella and other devastating diseases.

Until the late 1960s, tens of thousands of American children suffered crippling birth defects if their mothers had been exposed to rubella, popularly known as German measles, while pregnant; there was no vaccine and little understanding of how the disease devastated fetuses. In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus.

Meredith Wadman's masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who "owns" research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives.

With another frightening virus--measles--on the rise today, no medical story could have more human drama, impact, or urgency than The Vaccine Race.
Vaccinations: A Thoughtful Parent's Guide: How to Make Safe, Sensible Decisions about the Risks, Benefits, and Alternatives
Vaccinations: A Thoughtful Parent's Guide
How to Make Safe, Sensible Decisions about the Risks, Benefits, and Alternatives
Paperback      ISBN: 0892819316

- A balanced, comprehensive guide to routine childhood vaccinations that offers parents the information they need to make the right choices for their child.

- Fairly examines the pros and cons of this highly charged issue.

Deciding whether or when to vaccinate a child is one of the most important--and most difficult--health-care decisions a parent will ever make. The recent increase in the number of vaccinations recommended and the concurrent controversies about whether vaccinations are safe or even effective have left many parents confused and concerned.

Midwife, herbalist, and mother of four, Aviva Jill Romm sifts through the spate of current research on vaccine safety and efficacy and offers a sensible, balanced discussion of the pros and cons of each routine childhood vaccination. She presents the full spectrum of options available to parents: full vaccination on a standardized or individualized schedule, selective vaccination, or no vaccinations at all. Negotiating daycare and school requirements, dealing with other parents, and traveling with an unvaccinated child are covered in detail. The book also suggests ways to strengthen children's immune systems and maintain optimal health and offers herbal and homeopathic remedies for childhood ailments. Emphasizing that no single approach is appropriate for every child, the author guides parents as they make the choices that are right for their child.
Vacunas: Una Guí-A Para Padres Inteligentes: Cómo Tomar Decisiones Seguras Y Sensatas Sobre Los Riesgos, Beneficios, Y Alternativas
Vacunas: Una Guí-A Para Padres Inteligentes
Cómo Tomar Decisiones Seguras Y Sensatas Sobre Los Riesgos, Beneficios, Y Alternativas
Spanish    Paperback      ISBN: 1594770050

Decidir si uno quiere o cuando se debe vacunar un ni o, es una de las decisiones de la salud m s dif ciles y m s importantes que har un padre. El acrecimiento reci n del n mero de vacunas recomendadas y la controversia sobre su seguridad y efectividad ha dejado a muchos padres confusos y preocupados.

Partera, herbalista y madre de cuatro hijos, Aviva Jill romm, examina los datos corrientes sobre la seguridad y eficacia de vacunaci n y nos ofrece una discusi n equilibrada de cada tipo de vacuna para ni os. Nos presenta el espectro total de opciones para padres: un programa completo de vacunas, ya sea de norma o individual, vacunas selectivas, o no vacunar. La autora detalla como negociar con los del servicio de guarder a infantil y con los requerimientos del colegio, las relaciones con otros padres, y las consequencias de viajar con ni os que no han sido vacunados. El libro incluye sugerencias para fortalecer el sistema imunol gico de los ni os y mantener la salud, y recomienda remedios herbales y homeop ticos para enfermedades infantiles. La autora ofrece una gu a para ayudar a padres decidir lo que es apropiado para sus hijos y da nfasis en que no hay una sola manera para cada ni o.
Advanced Vaccine Research: Methods for the Decade of Vaccines
Advanced Vaccine Research
Methods for the Decade of Vaccines
Hardcover      ISBN: 1910190039

Since the publication of Fabio Bagnoli's and Rino Rappuoli's first book in 2011 (Vaccine Design: Innovative Approaches and Novel Strategies; ISBN 978 1 904455 74 5), the field of vaccinology has advanced significantly. The application of new sophisticated 'omics' technologies and the use of pioneering approaches have yielded a wealth of new data. This new book distills the most important new findings to provide a timely overview of the field. Written by leading experts in the field, each chapter affords a critical insight to a particular topic, reviews current research, discusses future direction, and aims to stimulate discussion. The provision of extensive reference sections in the book's chapters positively encourages readers to pursue the subject in greater detail. The book has retained the format of the 2011 book and is divided into two main parts. The first section explores in considerable depth the key innovations that are dramatically changing the field, both for preclinical as well as clinical vaccine research fields. Some of the topics covered include: the use of deep sequencing * cellular screens to interrogate the human T and B cell repertoires * comparative genomics to track bacterial pathogens * quantitative proteomics * structural biology * novel strategies for vaccine administration * T-cell inducing vaccines * etc. The second section focuses on diseases for which current medical treatment is not very effective, as well as diseases that could be either prevented or treated by vaccination. The book's contributors believe that these will be the vaccines of the future, the 'vaccines for 2020.' This book is essential reading for everyone working in vaccine R and D in academia, biotechnology companies, and the pharmaceutical industry, and it is a recommended volume for all microbiology libraries. *** Librarians: ebook available on ProQuest and EBSCO Subject: Microbiology, Vaccinology, Life Science

The Antivaccine Heresy: Jacobson V. Massachusetts and the Troubled History of Compulsory Vaccination in the United States
The Antivaccine Heresy
Jacobson V. Massachusetts and the Troubled History of Compulsory Vaccination in the United States
Hardcover      ISBN: 1580465374

Most people today celebrate vaccination as a great achievement, yet many nineteenth-century Americans opposed it, so much in fact that states had to make vaccination compulsory. In response, antivaccination societies formed all over the United States, lobbying state legislatures and bringing lawsuits to abolish these laws. One such lawsuit ultimately arrived at the United States Supreme Court, which upheld the laws in a landmark decision, Jacobson v. Massachusetts (1905). In this study, Karen Walloch examines the history of vaccine development in the United States, the laws put in place enjoining the practice, and the popular reaction against them. Walloch finds that at theend of the nineteenth century Americans had good reason to fear vaccination. Vaccines simply did not live up to claims made for their safety and effectiveness. They induced pain, disability, and grim or even fatal infections. Inthis critical history of the antivaccine movement and of Jacobson v. Massachusetts in particular, Walloch locates the beginnings of a legacy of doubt about vaccination -- one that affected legislation in all fifty states and is still very much alive today.

Karen Walloch is a historian who teaches at the University of Wisconsin-Madison.

Calling the Shots: Why Parents Reject Vaccines
Calling the Shots
Why Parents Reject Vaccines
1st Edition    Hardcover      ISBN: 147981279x

Winner, 2018 Donald W. Light Award for Applied Medical Sociology, American Sociological Association Medical Sociology Section

Winner, 2018 Distinguished Scholarship Award presented by the Pacific Sociology Association

Honorable Mention, 2017 ESS Mirra Komarovsky Book Award presented by the Eastern Sociological Society

Outstanding Book Award for the Section on Altruism, Morality, and Social Solidarity presented by the American Sociological Association

A rich, multi-faceted examination into the attitudes and beliefs of parents who choose not to immunize their children

The measles outbreak at Disneyland in December 2014 spread to a half-dozen U.S. states and sickened 147 people. It is just one recent incident that the medical community blames on the nation's falling vaccination rates. Still, many parents continue to claim that the risks that vaccines pose to their children are far greater than their benefits. Given the research and the unanimity of opinion within the medical community, many ask how such parents--who are most likely to be white, college educated, and with a family income over $75,000--could hold such beliefs.

For over a decade, Jennifer Reich has been studying the phenomenon of vaccine refusal from the perspectives of parents who distrust vaccines and the corporations that make them, as well as the health care providers and policy makers who see them as essential to ensuring community health. Reich reveals how parents who opt out of vaccinations see their decision: what they fear, what they hope to control, and what they believe is in their child's best interest. Based on interviews with parents who fully reject vaccines as well as those who believe in "slow vax," or altering the number of and time between vaccinations, the author provides a fascinating account of these parents' points of view.

Placing these stories in dialogue with those of pediatricians who see the devastation that can be caused by vaccine-preventable diseases and the policy makers who aim to create healthy communities, Calling the Shots offers a unique opportunity to understand the points of disagreement on what is best for children, communities, and public health, and the ways in which we can bridge these differences.
Calling the Shots: Why Parents Reject Vaccines
Calling the Shots
Why Parents Reject Vaccines
1st Edition    Paperback      ISBN: 1479874833

Winner, 2018 Donald W. Light Award for Applied Medical Sociology, American Sociological Association Medical Sociology Section

Winner, 2018 Distinguished Scholarship Award presented by the Pacific Sociology Association

Honorable Mention, 2017 ESS Mirra Komarovsky Book Award presented by the Eastern Sociological Society

Outstanding Book Award for the Section on Altruism, Morality, and Social Solidarity presented by the American Sociological Association

A rich, multi-faceted examination into the attitudes and beliefs of parents who choose not to immunize their children

The measles outbreak at Disneyland in December 2014 spread to a half-dozen U.S. states and sickened 147 people. It is just one recent incident that the medical community blames on the nation's falling vaccination rates. Still, many parents continue to claim that the risks that vaccines pose to their children are far greater than their benefits. Given the research and the unanimity of opinion within the medical community, many ask how such parents--who are most likely to be white, college educated, and with a family income over $75,000--could hold such beliefs.

For over a decade, Jennifer Reich has been studying the phenomenon of vaccine refusal from the perspectives of parents who distrust vaccines and the corporations that make them, as well as the health care providers and policy makers who see them as essential to ensuring community health. Reich reveals how parents who opt out of vaccinations see their decision: what they fear, what they hope to control, and what they believe is in their child's best interest. Based on interviews with parents who fully reject vaccines as well as those who believe in "slow vax," or altering the number of and time between vaccinations, the author provides a fascinating account of these parents' points of view.

Placing these stories in dialogue with those of pediatricians who see the devastation that can be caused by vaccine-preventable diseases and the policy makers who aim to create healthy communities, Calling the Shots offers a unique opportunity to understand the points of disagreement on what is best for children, communities, and public health, and the ways in which we can bridge these differences.
Combination Vaccines
Combination Vaccines
Hardcover      ISBN: 0896037177

A diverse team of leading experts comprehensively review the complex biology of a wide variety of vaccine combinations, as well as the technical, clinical, and regulatory aspects of their development. Topics covered range from the use of immunological correlates of efficacy, rather than efficacy per se, for the evaluation and licensure of vaccine combinations, to preserving a stable immunogenic mixture in appropriate containers according to accepted regulatory standards. Discussed in detail are the trivalent influenza vaccine, the pneumococcal polysaccharide vaccine, the MMR vaccine, the DTP vaccine and its combinations, and the quadrivalent rotavirus vaccine, all of which serve as models for the development of future combinations. Combination Vaccines: Development, Clinical Research, and Approval illuminates all the scientific, clinical, regulatory, and health care issues involved in the research, development, and human use of combination vaccines.


Combination Vaccines: Development, Clinical Research, and Approval
Combination Vaccines
Development, Clinical Research, and Approval
Paperback      ISBN: 1475748027

A diverse team of leading experts comprehensively review the complex biology of a wide variety of vaccine combinations, as well as the technical, clinical, and regulatory aspects of their development. Topics covered range from the use of immunological correlates of efficacy, rather than efficacy per se, for the evaluation and licensure of vaccine combinations, to preserving a stable immunogenic mixture in appropriate containers according to accepted regulatory standards. Discussed in detail are the trivalent influenza vaccine, the pneumococcal polysaccharide vaccine, the MMR vaccine, the DTP vaccine and its combinations, and the quadrivalent rotavirus vaccine, all of which serve as models for the development of future combinations. Combination Vaccines: Development, Clinical Research, and Approval illuminates all the scientific, clinical, regulatory, and health care issues involved in the research, development, and human use of combination vaccines.


Concepts in Vaccine Development
Concepts in Vaccine Development
Hardcover      ISBN: 3110148153