Genetic Code
Genome: The Autobiography of a Species in 23 Chapters
Genome
The Autobiography of a Species in 23 Chapters
Paperback      ISBN: 0060894083

Following in the tradition of James Gleick' Chaos, Matt Ridly vividly explores the most profound scientific discovery of the century--the mapping of the human genome. But what does that mean? In witty, clear language, Ridley answers this question for your students. Genome helps them understand what the human genetic code is, how it works, and how discoveries in the field of genetics are revolutionizing medicine, pharmaceuticals, business, politics, and our own sense of what it means to be human.

By picking one newly discovered gene from each of the twenty-three human chromosomes and telling its story, Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. Your students will discover:

- genes they share with bacteria

- genes that distinguish them from chimpanzees

- genes that may influence their intelligence

- genes that enable them to use language

- genes that allow them to remember

- genes that bring about diseases

- genes that battle with one another

- and more fascinating insights into their genetic makeup

Cutting through complicated scientific jargon, Ridley engages your students' minds and imaginations, exploring and making clear to them the applications of genetics: the search for understanding of where we come from and where we are headed.

Examining a scientific achievement on a parwith the splitting of the atom--and with asmany far-reaching implications--Genome will help students understand who they are as humans--and where they may be going.
The Double Helix: A Personal Account of the Discovery of the Structure of DNA
The Double Helix
A Personal Account of the Discovery of the Structure of DNA
Paperback      ISBN: 0393950751

In Criticism, which begins with "A Review of the Reviews" by Gunther Stent, other scientists and scholars reveal their own experiences and views of Watson's story. There are reviews by Philip Morrison, F. X. S., Richard C. Lewontin, Mary Ellmann, Robert L. Sinsheimer, John Lear, Alex Comfort, Jacob Bronowski, Conrad H. Waddington, Robert K. Merton, Peter M. Medawar, and Andr Lwoff; as well as three letters to the editor of Science by Max F. Perutz, M. H. F. Wilkins, and James D. Watson.
It Ain't Necessarily So: The Dream of the Human Genome and Other Illusions
It Ain't Necessarily So
The Dream of the Human Genome and Other Illusions
Paperback      ISBN: 0940322951

Is our nature--as individuals, as a species--determined by our evolution and encoded in our genes? If we unravel the protein sequences of our DNA, will we gain the power to cure all of our physiological and psychological afflictions and even to solve the problems of our society? Today biologists--especially geneticists--are proposing answers to questions that have long been asked by philosophy or faith or the social sciences. Their work carries the weight of scientific authority and attracts widespread public attention, but it is often based on what the renowned evolutionary biologist Richard Lewontin identifies as a highly reductive misconception: "the pervasive error that confuses the genetic state of an organism with its total physical and psychic nature as a human being."

In these nine essays covering the history of modern biology from Darwin to Dolly the sheep, all of which were originally published in The New York Review of Books, Lewontin combines sharp criticisms of overreaching scientific claims with lucid expositions of the exact state of current scientific knowledge--not only what we do know, but what we don't and maybe won't anytime soon. Among the subjects he discusses are heredity and natural selection, evolutionary psychology and altruism, nineteenth-century naturalist novels, sex surveys, cloning, and the Human Genome Project. In each case he casts an ever-vigilant and deflationary eye on the temptation to look to biology for explanations of everything we want to know about our physical, mental, and social lives.

These essays--several of them updated with epilogues that take account of scientific developments since they were first written--are an indispensable guide to the most controversial issues in the life sciences today.

The second edition of this collection includes new essays on genetically modified food and the completion of the Human Genome Project. It is an indispensable guide to the most controversial issues in the life sciences today.
Anatomy of Gene Regulation
Anatomy of Gene Regulation
Hardcover      ISBN: 0521800307

Anatomy of Gene Regulation is the first book to present the parts and processes of gene regulation at the three-dimensional level. Vivid structures of nucleic acids and their companion proteins are revealed in full-color, three dimensional form. Beginning with a general introduction to three-dimensional structures, the book looks at the organization of the genome, the structure of DNA, DNA replication and transcription, splicing, protein synthesis, and ultimate protein death. This concise and unique synthesis and its accompanying web site offer insight into gene regulation, and into the development of methods to interfere with regulation at diseased states.

Anatomy of Gene Regulation: A Three-Dimensional Structural Analysis
Anatomy of Gene Regulation
A Three-Dimensional Structural Analysis
Paperback      ISBN: 0521804744

Anatomy of Gene Regulation is the first book to present the parts and processes of gene regulation at the three-dimensional level. Vivid structures of nucleic acids and their companion proteins are revealed in full-color, three dimensional form. Beginning with a general introduction to three-dimensional structures, the book looks at the organization of the genome, the structure of DNA, DNA replication and transcription, splicing, protein synthesis, and ultimate protein death. This concise and unique synthesis and its accompanying web site offer insight into gene regulation, and into the development of methods to interfere with regulation at diseased states.

Chance in the House of Fate: A Natural History of Heredity
Chance in the House of Fate
A Natural History of Heredity
Paperback      ISBN: 0618219099

Award-winning science writer Jennifer Ackerman investigates the endless mysteries of genetics, offering an elegant natural history of humanity as seen through the lens of our genes and cells. Combining the gifts of vision and language with in-depth knowledge, Ackerman explores the ways in which, at the most fundamental level, humans are genetically linked to every part of the natural world. CHANCE IN THE HOUSE OF FATE is a rich and often personal tour through the surprising turns of heredity, informed by the ways genetic inheritance has affected Ackerman's own life. From a younger sister's profound retardation and her mother's illness to the births of her own healthy daughters, Ackerman reveals her own experiences as telling touchpoints, ultimately illuminating the the hidden biological connections among all forms of life.

Comparative Genomics
Comparative Genomics
Hardcover      ISBN: 0412830809

Since the advent of the Human Genome Project, an increasing number of disease-causing genes have been discovered and, in some cases, genetic tests developed. However, this is only the first step. The second, much larger phase is the analysis of the total sequence. What does the rest of the DNA do? The answer to this question will be determined by computer prediction, expression profiling, and comparative genome analysis.
Comparative Genomics covers such topics as identifying novel genes, determining gene function, control sequences, and developmental switches. The book aims to demonstrate how different approaches taken with model organisms, such as mutation studies, expression profiling of cDNAs, in situ localization of message and comparative genome analysis (both at the gene and nucleotide level) will aid in our understanding of the results coming out of the Human Genome Project and contribute significantly to our understanding of how genes function.

Comparative Genomics: Empirical and Analytical Approaches to Gene Order Dynamics, Map Alignment and the Evolution of Gene Families
Comparative Genomics
Empirical and Analytical Approaches to Gene Order Dynamics, Map Alignment and the Evolution of Gene Families
Hardcover      ISBN: 0792365836

A comprehensive account of genomic rearrangement, focusing on the mechanisms of inversion, translocation, gene and genome duplication and gene transfer and on the patterns that result from them in comparative maps. Includes analyses of genomic sequences in organelles, prokaryotes and eukaryotes as well as comparative maps of the nuclear genomes in higher plants and animals. The book showcases a variety of algorithmic and statistical approaches to rearrangement and map data.

Comparative Genomics
Comparative Genomics
Paperback      ISBN: 1461371074

Since the advent of the Human Genome Project, an increasing number of disease-causing genes have been discovered and, in some cases, genetic tests developed. However, this is only the first step. The second, much larger phase is the analysis of the total sequence. What does the rest of the DNA do? The answer to this question will be determined by computer prediction, expression profiling, and comparative genome analysis.
Comparative Genomics covers such topics as identifying novel genes, determining gene function, control sequences, and developmental switches. The book aims to demonstrate how different approaches taken with model organisms, such as mutation studies, expression profiling of cDNAs, in situ localization of message and comparative genome analysis (both at the gene and nucleotide level) will aid in our understanding of the results coming out of the Human Genome Project and contribute significantly to our understanding of how genes function.

Computational Genetics and Genomics: Tools for Understanding Disease
Computational Genetics and Genomics
Tools for Understanding Disease
Hardcover      ISBN: 1588291871

Ultimately, the quality of the tools available for genetic analysis and experimental disease models will be assessed on the basis of whether they provide new information that generates novel treatments for human disease. In addition, the time frame in which genetic discoveries impact clinical practice is also an important dimension of how society assesses the results of the significant public financial investment in genetic research. Because of the investment and the increased expectation that new tre- ments will be found for common diseases, allowing decades to pass before basic discoveries are made and translated into new therapies is no longer acceptable. Computational Genetics and Genomics: Tools for Understanding Disease provides an overview and assessment of currently available and developing tools for genetic analysis. It is hoped that these new tools can be used to identify the genetic basis for susceptibility to disease. Although this very broad topic is addressed in many other books and journal articles, Computational Genetics and Genomics: Tools for Understanding Disease focuses on methods used for analyzing mouse genetic models of biomedically - portant traits. This volume aims to demonstrate that commonly used inbred mouse strains can be used to model virtually all human disea- related traits. Importantly, recently developed computational tools will enable the genetic basis for differences in disease-related traits to be rapidly identified using these inbred mouse strains. On average, a decade is required to carry out the development process required to demonstrate that a new disease treatment is beneficial.